NFL Week 1 weirdness? Examining which opening game could be this year's big upset
Michael Middlehurst-Schwartz
USA TODAY
SportsGrid
NFL 2026: Detroit faces Buffalo in Week 2. Amazon Prime broadcasts games on Black Friday and Christmas Eve. Craig Mish discusses the latest sports headlines.
The NFL has made it clear that it intends to engineer memorable matchups for the opening week of the season, saving its prime-time slots for marquee teams. Sometimes, though, the most captivating results come from unexpected games.
Clemson Tigers offensive lineman Blake Miller is selected by the Detroit Lions as the No. 17 pick during the NFL Draft at Acrisure Stadium on April 23 in Pittsburgh.
Cleveland Browns defensive end Myles Garrett, left, tries to get past Pittsburgh Steelers guard Spencer Anderson as quarterback Aaron Rodgers looks to throw during the second half of a Dec. 28 game at Huntington Bank Field in Cleveland.
Clemson Tigers offensive lineman Blake Miller is selected by the Detroit Lions as the No. 17 pick during the NFL Draft at Acrisure Stadium on April 23 in Pittsburgh.
Cleveland Browns defensive end Myles Garrett, left, tries to get past Pittsburgh Steelers guard Spencer Anderson as quarterback Aaron Rodgers looks to throw during the second half of a Dec. 28 game at Huntington Bank Field in Cleveland.