Novel ideas outmaneuver a novel virus

kAmqFE 4C62E:G6 A6@A=6 2C6 7:?5:?8 D276 H2JD E@ >@G6 7@CH2C5]k^Am

kAmp 8@@5 6I2>A=6 H2D k2 9C67lQ9EEADi^^>25:D@?]4@>^HD;^6?E6CE2:?>6?E^5:?:?8^>25:D@?\C6DE2FC2?ED\2==@H65\E@\6IA2?5\@FE5@@C\5:?:?8\5FC:?8\4@G:5\`h\A2?56>:4^2CE:4=60`6`4bh67\55`c\dhg3\3c5_\eg7eada72h53]9E>=Q E2C86ElQ03=2?<Qm|25:D@?’D 6>6C86?4J @C56Ck^2m =2DE H66< 2==@H:?8 DECF88=:?8 C6DE2FC2?ED E@ >@G6 >@C6 E23=6D @FED:56 @?E@ E96 D:56H2=<D 2?5 A2C<:?8 DE2==D D@ 5:?6CD 42? 62E 2 D276 5:DE2?46 2A2CE] %96 4:EJ >2J 8@ 7FCE96C 3J 4=@D:?8 F?56CFD65 DEC66ED s@H?E@H? E@ 2==@H 7@C 6G6? >@C6 DA246] %92E H:== 96=A @77D6E E96 adT @44FA2?4J =:>:E s2?6 r@F?EJ :D 6?7@C4:?8 7@C 62E6C:6D :?5@@CD]k^Am

kAmxE’D 2 D>2CE :562 E@ ;F>A\DE2CE 3FD:?6DD6D D9FE 5@H? 7@C >@?E9D 3642FD6 @7 r~'xs\`h[ E96 62D:=J DAC625 C6DA:C2E@CJ 5:D62D6 E92E 92D :?764E65 >@C6 E92? `g[___ 2?5 <:==65 ?62C=J e__ 24C@DD (:D4@?D:?]k^Am

kAm(6’5 8@ 6G6? 7FCE96C] w@H 23@FE E2<:?8 E96 3FD6D @77 $E2E6 $EC66E 2?5 EFC?:?8 E96 6?E:C6 DEC6E49 @7 A2G6>6?E 36EH66? E96 DE2E6 r2A:E@= 2?5 E96 &(\|25:D@? 42>AFD k2 9C67lQ9EEADi^^>25:D@?]4@>^HD;^@A:?:@?^65:E@C:2=^E9:?<\3:8\23@FE\7FEFC6\@7\DE2E6\DEC66E^2CE:4=605f`4h4a3\_63a\d6e_\h4c`\ab55`a4c63bc]9E>=Q E2C86ElQ03=2?<Qm:?E@ 2 AF3=:4 AC@>6?256k^2mn %92E H@F=5 4C62E6 =@ED @7 6IEC2 DA246 7@C 32CD[ C6DE2FC2?ED[ C6E2:=6CD 2?5 E96 AF3=:4]k^Am

kAmw6C6’D 2?@E96C :?86?:@FD >@G6 E92E =65 E@ 2 D276 DAC:?8 6=64E:@? :? |25:D@? H:E9@FE =@?8 =:?6D 2E E96 A@==Di q6D:56D 6?4@FC28:?8 >@DE A6@A=6 E@ G@E6 7C@> 9@>6 FD:?8 23D6?E66 32==@ED[ |25:D@?’D 4=6C< k2 9C67lQ9EEADi^^>25:D@?]4@>^HD;^@A:?:@?^65:E@C:2=^5@?E\=6E\H:D4@?D:?\364@>6\E96\7=@C:52\@7\E96\a_a_\C246\7@C\AC6D:56?E^2CE:4=60fac233dg\be_6\de6_\gadf\d24e4eg36cg3]9E>=Q E2C86ElQ03=2?<QmC64CF:E65 =2:5\@77 32CE6?56CDk^2m — H9@ E6?5 E@ 36 J@F?86C 2?5 =6DD DFD46AE:3=6 E@ r~'xs\`h — E@ 7:== :? 7@C @=56C A@== H@C<6CD H9@ 5:5?’E 766= D276 DE277:?8 :?\A6CD@? G@E:?8 DE2E:@?D]k^Am

kAmxE H2D 2 ?@G6= H@C<2C@F?5 E92E 2==@H65 @FC 56>@4C24J — H9:49 :D 6DD6?E:2= — E@ AC@4665 H:E9@FE C64<=6DD=J ;6@A2C5:K:?8 AF3=:4 962=E9]k^Am

kAm(:D4@?D:? 2?5 @FC ?2E:@? ?665 >@C6 8@@5 :562D E@ 7:89E 2?5 @FE>2?6FG6C E9:D 5:D62D6 F?E:= 36EE6C EC62E>6?E @C 2 G244:?6 2C6 56G6=@A65] x7 J@F <?@H @7 2 4@>>F?:EJ[ 3FD:?6DD @C 8C@FA E92E’D 7:8FC65 @FE 2? :??@G2E:G6 H2J E@ 86E E9:?8D 5@?6[ A=62D6 =6E FD <?@H] (6 H2?E E@ D92C6 E96 36DE :562D H:E9 E96 C6DE @7 E96 DE2E6]k^Am

kAm$6?5 J@FC 6I2>A=6D E@ k2 9C67lQ>2:=E@iHD;@A:?6o>25:D@?]4@>Q E2C86ElQ03=2?<QmHD;@A:?6o>25:D@?]4@>k^2m]k^Am

kAm(96? EH@ $F? !C2:C:6 ?6:893@CD — y@6 {29E: 2?5 vC68 %9@>D@? — H6C6 C6DE=6DD 2E 9@>6 5FC:?8 E96 96:89E @7 E96 A2?56>:4[ E96J k2 9C67lQ9EEADi^^>25:D@?]4@>^HD;^@A:?:@?^65:E@C:2=^96=A\362E\E96\4@C@?2G:CFD\;F>A\2C@F?5^2CE:4=60`66ed``_\h6gf\d5f`\gc_5\5d45ac4`56ah]9E>=Q E2C86ElQ03=2?<Qm@C82?:K65 2 “yF>A pC@F?5”k^2m H:E9 ?6:893@CD] %96J ;F>A65 FA 2?5 5@H? :? E96:C 5C:G6H2JD E@ E96 `hha w@FD6 @7 !2:? 9:E D@?8 “yF>A pC@F?5[” >:>:4<:?8 H92E 92AA6?D 2E (:D4@?D:? 7@@E32== 82>6D 2E E96 6?5 @7 E96 E9:C5 BF2CE6C :? r2>A #2?52== DE25:F>] xE H2D 2 7F? 5:G6CD:@? E92E 8C6H :?E@ 2 DE2E6H:56 H66<=J 6G6?E] |@C6 E92? `__ C25:@ DE2E:@?D A=2J65 E96 D@?8 2E E96 D2>6 E:>6 $2EFC52J 27E6C?@@?D[ H:E9 2D >2?J 2D k2 9C67lQ9EEADi^^HHH]72463@@<]4@>^8C@FAD^;F>A2C@F?5H:D4@?D:?Q E2C86ElQ03=2?<Qm`a_[___ A2CE:4:A2?EDk^2m] %96J 6G6? C2:D65 >@?6J 7@C 492C:EJ]k^Am

kAm(96? qC2E u6DE 42?46=65 :ED 8:2?E 76DE:G2= =2DE H66<6?5 3642FD6 @7 r~'xs\`h[ @C82?:K6CD k2 9C67lQ9EEADi^^>25:D@?]4@>^HD;^@A:?:@?^65:E@C:2=^3FJ\2\G:CEF2=\3C2E\7@C\492C:EJ^2CE:4=607ffe4h6`\bdaa\d766\354`\gch44dg3bedg]9E>=Q E2C86ElQ03=2?<Qm=2F?4965 2 G:CEF2= D2=6k^2m @7 3C2ED 2?5 4C27E 366C E@ C2:D6 >@?6J 7@C `ad ?@?AC@7:ED E92E @E96CH:D6 H@F=5 92G6 =@DE E96:C 3:886DE 7F?5C2:D6C @7 E96 J62C] $@ 72C[ 5@?2E:@?D 92G6 C624965 Sf_[___]k^Am

kAmx? $EFC86@? q2J[ 23@FE `g_ >:=6D ?@CE962DE @7 |25:D@? :? s@@C r@F?EJ[ 2 k2 9C67lQ9EEADi^^5@@C4@F?EJAF=D6]4@>^DEFC86@?\32JD\a_a_\4@>>6?46>6?E\A=2?DQ E2C86ElQ03=2?<Qm3@2E AC@46DD:@?k^2m $2EFC52J C6A=2465 8C25F2E:@? 46C6>@?:6D] t249 8C25F2E6 H2D 42==65 E@ 2 A:6C 2E 2 =@42= >2C:?2 2?5[ 27E6C C646:G:?8 2 5:A=@>2[ 3@2C565 2 3@2E 7@C 2 D9@CE C:56 :? E96 32J]k^Am

kAm%6== FD 23@FE E96 4=6G6C :562D J@F’G6 D66? @C 962C5 23@FE 24C@DD (:D4@?D:?] t>2:= FD 2E k2 9C67lQ>2:=E@iHD;@A:?6o>25:D@?]4@>Q E2C86ElQ03=2?<QmHD;@A:?6o>25:D@?]4@>k^2m] (6’== 9:89=:89E :? 2 7FEFC6 65:E@C:2= 2== E96 :?G6?E:G6 H2JD A6@A=6 2C6 42CCJ:?8 @? E96:C =:G6D 56DA:E6 E96 A2?56>:4]k^Am

kA 4=2DDlQE?4>D\:?=:?6\=:?<Qmk2 9C67lQ9EEADi^^>25:D@?]4@>^E?4>D^2DD6E^65:E@C:2=^5d6be_bg\b3`a\d`__\332e\cb`h5h`_h_74Qmr6?E6C $E286 H:E9 |:=7C65 2?5 w2?5Dk^2mk^Am